...the initial results did not indicate any sign of brain damage, but the neurologist warned us that the results of hypoxia (lack
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...tract. When mitochondria are inefficient or damaged, reactive oxygen species (ROS) increase. Anti-oxidant capacity decreases and further damage to the PDC ensues.
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...in that situation: the vessels’ endothelium gets damaged, leading to various blood flow problems including micro-clotting. This further aggravates the tissue hypoxia
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...as I see this pattern, brainstem degradation>thalamic involvement, I immediately think dysautonomia>beriberi>thiamine deficiency>mito-hypoxia>disrupted immune function>inflammation overkill>leaky BBB >leaky junctions. Then a few,
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Talking About Thiamine Again
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...the ability to utilize oxygen in the cells diminishes. The cell level hypoxia then drives all sorts of compensatory reactions that, when
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...of cellular hypoxia sets in; one that activates inflammatory pathways, and ultimately, the shift in tale tell shift energy production associated with
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...the aspirin had sent a signal into it, implying undue sensitivity of the cells receiving the signal. That kind of hypersensitivity reflects
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...deficiency mitochondria potentially making less ATP which is needed to make TPP. Also, there is some evidence that hypoxia decreases the production
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